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In bodybuilding, testosterone is predominantly used in bulking cycles to add large amounts of muscle and strength; however it’s also utilized in cutting cycles to retain muscle hypertrophy. When injected correctly, it can be argued that testosterone is one of the safest steroids available. Testosterone causes hefty gains in muscle size (20-30lbs) and remains as one of the most popular steroids in bodybuilding; despite coming to market over 80 years ago. If injected incorrectly, any steroid or medication can be dangerous (or fatal). However, there is oral testosterone available (undecanoate) for those wanting to avoid needles. Oral testosterone is less commonly used in bodybuilding, compared to injectables, due to its higher market price. Testosterone poses little to no hepatic concern (liver stress), due to it being an injectable and thus entering the blood stream immediately; instead of the liver having to filter it. Oral testosterone (undecanoate) is also safe for the liver, with it being absorbed via the intestinal lymphatic route; thus preventing hepatic strain. One study gave 2,800mg per week of testosterone undecanoate to male subjects for 21 days (5); yet none of them experienced any hepatotoxic stress, despite such an exceedingly large dose. Testosterone is likely to increase blood pressure, due to a redistribution of HDL/LDL cholesterol levels. However, such cholesterol fluctuations are mild, compared to other anabolic steroids, safest muscle building steroid. There are a couple of reasons why testosterone doesn’t negatively affect blood pressure significantly. Firstly, it converts to estrogen, with the female hormone having a positive effect on blood lipids. Secondly, testosterone doesn’t pass through the liver, thus failing to stimulate hepatic lipase, an enzyme which can skew cholesterol levels in the wrong direction. There is evidence oral testosterone may even improve cardiovascular health, when therapeutic doses are administered in overweight men (6). This however is likely to be correlative, with a reduction in fat mass likely being the culprit for such reductions in BP. For most bodybuilders taking moderate to high dosages of testosterone, blood pressure will rise; with the severity depending on the dose and cycle duration. In research, 280mg/week of testosterone enanthate had a very slight negative effect on HDL cholesterol, after 12 weeks (7). Meanwhile, 600mg/week caused a reduction of 21%. Note : Taking an AI (aromatase inhibitor) will further spike blood pressure, by inhibiting testosterone to estrogen conversion, thus further decreasing HDL levels. Testosterone has the ability to cause gynecomastia and water retention, due to its estrogenic nature; however a SERM (such as nolvadex) significantly reduces the chances of gyno forming. Incidents of gynecomastia are particularly rare, when combining low doses of testosterone with a SERM. Androgenic side effects, such as: hair loss on the scalp, prostate enlargement and acne are possible on testosterone. Such side effects inspired Dr Ziegler to create dianabol, after understanding the Soviet strongmen had to use urinary catheters, as a result of cycling testosterone in the Olympic games. Thus, dianabol was formulated to be less androgenic than testosterone ‘ yet more anabolic.
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Steroid medicines are man-made but are similar to these natural hormones. Steroids used to treat disease are called corticosteroids. They are different to the anabolic steroids which some athletes and bodybuilders use. Anabolic steroids have very different effects. Steroids are available as tablets, soluble tablets, and liquids (solutions), creams, ointments, inhalers and injections. Types of oral steroids. The most commonly used group is glucocorticoids. This group includes steroids such as: The other group is called mineralocorticoids. This is the type usually used for replacing steroids the body isn’t producing itself, and the common one used is fludrocortisone. They usually come as tablets, but some also come as dispersible (dissolvable) tablets or solutions. What are oral steroids usually prescribed for? Oral steroids are used to treat a large number of conditions. Some examples include: Inflammatory bowel diseases (for example, Crohn’s disease, ulcerative colitis). Autoimmune diseases (for example, systemic lupus erythematosus (SLE), autoimmune hepatitis). Relapses that occur in multiple sclerosis. Joint and muscle diseases (for example, rheumatoid arthritis, polymyalgia rheumatica). Chronic obstructive pulmonary disease (COPD). They are also used to treat the effects of some cancers. In addition they can be prescribed as replacement treatment for people whose own natural steroids are lacking (for example, in Addison’s disease, congenital adrenal hyperplasia and hypopituitarism). What is the dose, safest muscle building steroid. This will vary with individual steroids and with the condition for which they are prescribed. For short courses, usually a relatively high dose is prescribed each day, for a few days or a week or so, and then stopped abruptly at the end of the course. If taken for more than three weeks, the dose will need to be tailed off gradually. For those who have to take steroids for a longer time, a common treatment plan is to start with a high dose to control symptoms. Often the dose is then slowly reduced to a lower daily dose that keeps symptoms away. undefined
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