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In these final analyses, I’ve decided to pool the data from Kouri and from Brennan’s comparison of drug-free lifters vs. I personally think that Brennan’s data is better for elucidating long-term hypertrophy differences, but I ultimately feel slightly better analyzing data from larger samples, and the gap between the users and non-users was pretty similar in both comparisons anyways (3. Using these average numbers, the non-users had an FFMI of 22. Now we can answer a few burning questions: 1) How jacked can someone possibly get drug-free? The most epistemically honest answer is that I don’t know, no one knows, and there’s really not a good way TO know. We have a pretty good idea of how jacked a few people got before steroids burst onto the scene, but like I said in the intro, odds are horrendously low that any of the members of that tiny subculture attained the absolute pinnacle of drug-free muscular development. If people have continued to improve in every other physical domain to a degree that can’t be solely attributed to performance enhancing drugs, I can’t see a good reason why bodybuilding would be an exception. Unfortunately, it’s also impossible to establish a maximum degree of drug-free muscularity with modern data. Quite simply, drug-testing doesn’t catch everyone (and without out-of-competition testing, it only catches people who are really dumb), and it’s easy for someone to claim they’re drug-free without ever having been drug-tested. You can never be 100% confident that an individual ‘ much less everyone in a group ‘ is, in fact, drug free. In other words, it’s impossible to know for sure. Some people like to claim that an FFMI of 25 is a hard cutoff, based on Kouri’s study, because the researchers didn’t find any drug-free people in their sample with an FFMI over 25. However, this is a very naive way to approach the question, because: Their drug-free sample was only 74 people. When you’re asking how big someone can get drug-free, you’re inherently asking about the outliers. In a sample of 74 people, your odds of finding someone at the limits of any trait or ability are horrendously low; you’re probably not going to find someone who runs a sub-10 second 100m dash, or who’s 7 feet tall, or who has Einstein’s IQ. Even in a 74-person sample of exceptionally fast people, exceptionally tall people, or exceptionally smart people, you’re probably not going to find the next Usain Bolt (100m dash of 9. The researchers DO note that a handful of their subjects were successful natural bodybuilders or strength athletes, but since they didn’t have an experience requirement, it’s highly unlikely that all (or even most) of the subjects were at or near their drug-free muscular potential. Even if they were, it’s still very unlikely you’d find someone at the limits of what could be attained drug-free. 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